Jul 26

Tobias Reichlin.

The evaluation of areas beneath the ROC curves was performed as suggested by DeLong et al.22 All hypothesis assessment was two-tailed, and P values of significantly less than 0.05 were considered to indicate statistical significance. All statistical analyses were performed with the use of SPSS for Windows, version 15.0 , and MedCalc software program, version . Results Characteristics of the Patients Baseline values from all five assays were available for 718 of the 786 consecutive patients; values from less than five assays had been available for the remaining 68 patients.Researchers created the SPRINT clinical trial to see if pushing blood pressure even lower would improve people’s health. Doctors have long debated the merits of controlling blood pressure more tightly than recommended, Fonarow said. ‘Many physicians, and even those serving on certain guideline writing groups, had been highly skeptical that decreasing systolic blood pressure to the 120 level would present additional benefits, be safe and sound, and be very well tolerated,’ he said. The SPRINT experts randomly divided the analysis participants into two groups, one whose blood circulation pressure was controlled to the present suggestions and another whose blood circulation pressure was kept at significantly less than 120. Between 2010 and 2013, the typical group took an average of two different blood pressure medications to meet the recommended goal, as the intensive treatment group received an average of three medicines to bring their blood circulation pressure farther down.